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Ultrasound directs a transposase system for durable hepatic gene delivery in mice

Our aim was to evaluate the delivery of transposase-based vectors by Ultrasound Targeted Microbubble Destruction (UTMD) in mice. DNA vectors were attached to cationic lipid microbubbles (1-3 μm in diameter), injected intravenously, and delivered to the liver by destruction of the carrier bubbles wit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Anderson, Cynthia D, Urschitz, Johann, Khemmani, Mark, Owens, Jesse B, Moisyadi, Stefan, Shohet, Ralph V, Walton, Chad B
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838570/
https://ncbi.nlm.nih.gov/pubmed/24035623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ultrasmedbio.2013.07.002
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