Model of effectively neutral mutations in which selective constraint is incorporated
Based on the idea that selective neutrality is the limit when the selective disadvantage becomes indefinitely small, a model of neutral (and nearly neutral) mutations is proposed that assumes that the selection coefficient (s′) against the mutant at various sites within a cistron (gene) follows a Γ...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autore principale: | |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1979
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383841/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/16592684/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.7.3440 |
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