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Model of effectively neutral mutations in which selective constraint is incorporated

Based on the idea that selective neutrality is the limit when the selective disadvantage becomes indefinitely small, a model of neutral (and nearly neutral) mutations is proposed that assumes that the selection coefficient (s′) against the mutant at various sites within a cistron (gene) follows a Γ...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Yazar: Kimura, Motoo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 1979
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383841/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/16592684/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.7.3440
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