Alpha Interferon Restricts Human T-Lymphotropic Virus Type 1 and 2 De Novo Infection through PKR Activation

Type I interferon (IFN-I) inhibits the replication of different viruses. However, the effect of IFN-I on the human T-lymphotropic virus type 1 (HTLV-1) viral cycle is controversial. Here, we investigated the consequences of IFN-α addition for different steps of HTLV-1 and HTLV-2 infection. We first...

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Detalhes bibliográficos
Main Authors: Cachat, Anne, Chevalier, Sébastien Alain, Alais, Sandrine, Ko, Nga Ling, Ratner, Lee, Journo, Chloé, Dutartre, Hélène, Mahieux, Renaud
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838277/
https://ncbi.nlm.nih.gov/pubmed/24089560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02758-13
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