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Dendritic cell maturation, but not type I interferon exposure, restricts infection by HTLV-1, and viral transmission to T-cells

Human T lymphotropic Virus type 1 (HTLV-1) is the etiological agent of Adult T cell Leukemia/Lymphoma (ATLL) and HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP). Both CD4(+) T-cells and dendritic cells (DCs) infected with HTLV-1 are found in peripheral blood from HTLV-1 carriers....

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Rizkallah, Gergès, Alais, Sandrine, Futsch, Nicolas, Tanaka, Yuetsu, Journo, Chloé, Mahieux, Renaud, Dutartre, Hélène
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5413061/
https://ncbi.nlm.nih.gov/pubmed/28426803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006353
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