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Truncation and Sequence Shuffling of Segment 6 Generate Replication-Competent Neuraminidase-Negative Influenza H5N1 Viruses

Influenza viruses are highly genetically variable and escape from immunogenic pressure by antigenic changes in their surface proteins, referred to as “antigenic drift” and “antigenic shift.” To assess the potential genetic plasticity under strong selection pressure, highly pathogenic avian influenza...

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Detalhes bibliográficos
Main Authors: Kalthoff, Donata, Röhrs, Susanne, Höper, Dirk, Hoffmann, Bernd, Bogs, Jessica, Stech, Jürgen, Beer, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838276/
https://ncbi.nlm.nih.gov/pubmed/24109212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02244-13
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