Truncation and Sequence Shuffling of Segment 6 Generate Replication-Competent Neuraminidase-Negative Influenza H5N1 Viruses

Influenza viruses are highly genetically variable and escape from immunogenic pressure by antigenic changes in their surface proteins, referred to as “antigenic drift” and “antigenic shift.” To assess the potential genetic plasticity under strong selection pressure, highly pathogenic avian influenza...

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Autores principales: Kalthoff, Donata, Röhrs, Susanne, Höper, Dirk, Hoffmann, Bernd, Bogs, Jessica, Stech, Jürgen, Beer, Martin
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2013
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838276/
https://ncbi.nlm.nih.gov/pubmed/24109212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02244-13
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