The T Antigen Locus of Merkel Cell Polyomavirus Downregulates Human Toll-Like Receptor 9 Expression

Establishment of a chronic infection is a key event in virus-mediated carcinogenesis. Several cancer-associated, double-stranded DNA (dsDNA) viruses act via their oncoproteins to downregulate Toll-like receptor 9 (TLR9), a key receptor in the host innate immune response that senses viral or bacteria...

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Bibliographische Detailangaben
Hauptverfasser: Shahzad, Naveed, Shuda, Masahiro, Gheit, Tarik, Kwun, Hyun Jin, Cornet, Iris, Saidj, Djamel, Zannetti, Claudia, Hasan, Uzma, Chang, Yuan, Moore, Patrick S., Accardi, Rosita, Tommasino, Massimo
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838112/
https://ncbi.nlm.nih.gov/pubmed/24067965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01786-13
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