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T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus

Merkel cell polyomavirus (MCV) is a virus discovered in our laboratory at the University of Pittsburgh that is monoclonally integrated into the genome of ≈80% of human Merkel cell carcinomas (MCCs). Transcript mapping was performed to show that MCV expresses transcripts in MCCs similar to large T (L...

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Detalhes bibliográficos
Main Authors: Shuda, Masahiro, Feng, Huichen, Kwun, Hyun Jin, Rosen, Steven T., Gjoerup, Ole, Moore, Patrick S., Chang, Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2551627/
https://ncbi.nlm.nih.gov/pubmed/18812503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806526105
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