Merkel Cell Polyomavirus Downregulates N-myc Downstream-Regulated Gene 1, Leading to Cellular Proliferation and Migration

Merkel cell polyomavirus (MCPyV) is the first human polyomavirus etiologically associated with Merkel cell carcinoma (MCC), a rare and aggressive form of skin cancer. Similar to other polyomaviruses, MCPyV encodes early T antigen genes, viral oncogenes required for MCC tumor growth. To identify the...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Gupta, Purnima, Shahzad, Naveed, Harold, Alexis, Shuda, Masahiro, Venuti, Assunta, Romero-Medina, Maria Carmen, Pacini, Laura, Brault, Lise, Robitaille, Alexis, Taverniti, Valerio, Hernandez-Vargas, Hector, Durand, Geoffroy, Le Calvez-Kelm, Florence, Gheit, Tarik, Accardi, Rosita, Tommasino, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000982/
https://ncbi.nlm.nih.gov/pubmed/31694959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00899-19
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