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An FtsZ-Targeting Prodrug with Oral Antistaphylococcal Efficacy In Vivo
The bacterial cell division protein FtsZ represents a novel antibiotic target that has yet to be exploited clinically. The benzamide PC190723 was among the first FtsZ-targeting compounds to exhibit in vivo efficacy in a murine infection model system. Despite its initial promise, the poor formulation...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3837898/ https://ncbi.nlm.nih.gov/pubmed/24041882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01016-13 |
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