Investigation of the Interactions between Methadone and Elvitegravir-Cobicistat in Subjects Receiving Chronic Methadone Maintenance

Interactions between HIV and opioid dependence therapies are known to occur. We sought to determine if such interactions occurred between methadone and elvitegravir boosted with cobicistat (EVG/COBI). We performed a within-subject open-label pharmacokinetic and pharmacodynamic study of 11 HIV-serone...

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Bibliografiske detaljer
Main Authors: Bruce, R. Douglas, Winkle, P., Custodio, J. M., Wei, X., Rhee, M. S., Kearney, B. P., Ramanathan, S., Friedland, Gerald H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2013
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837895/
https://ncbi.nlm.nih.gov/pubmed/24080665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01229-13
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