Investigation of the Interactions between Methadone and Elvitegravir-Cobicistat in Subjects Receiving Chronic Methadone Maintenance

Interactions between HIV and opioid dependence therapies are known to occur. We sought to determine if such interactions occurred between methadone and elvitegravir boosted with cobicistat (EVG/COBI). We performed a within-subject open-label pharmacokinetic and pharmacodynamic study of 11 HIV-serone...

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Detalhes bibliográficos
Main Authors: Bruce, R. Douglas, Winkle, P., Custodio, J. M., Wei, X., Rhee, M. S., Kearney, B. P., Ramanathan, S., Friedland, Gerald H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837895/
https://ncbi.nlm.nih.gov/pubmed/24080665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01229-13
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