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Whole-Cell Screening-Based Identification of Inhibitors against the Intraphagosomal Survival of Mycobacterium tuberculosis

We describe here an efficient strategy that employs whole-cell-based screening and further short listing of the compounds by cytotoxicity- and fluorescence-based intracellular assays, resulting in potential bactericidal hits against the growth of Mycobacterium tuberculosis in broth culture as well a...

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Detalhes bibliográficos
Main Authors: Khare, Garima, Kumar, Praveen, Tyagi, Anil K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837871/
https://ncbi.nlm.nih.gov/pubmed/24060878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01444-13
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