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Identification of Mycobacterium tuberculosis BioA inhibitors by using structure-based virtual screening
BACKGROUND: 7,8-Diaminopelargonic acid synthase (BioA), an enzyme of biotin biosynthesis pathway, is a well-known promising target for anti-tubercular drug development. METHODS: In this study, structure-based virtual screening was employed against the active site of BioA to identify new chemical ent...
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| Gepubliceerd in: | Drug Des Devel Ther |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Dove Medical Press
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5935190/ https://ncbi.nlm.nih.gov/pubmed/29750019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S144240 |
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