Identification of Mycobacterium tuberculosis BioA inhibitors by using structure-based virtual screening

BACKGROUND: 7,8-Diaminopelargonic acid synthase (BioA), an enzyme of biotin biosynthesis pathway, is a well-known promising target for anti-tubercular drug development. METHODS: In this study, structure-based virtual screening was employed against the active site of BioA to identify new chemical ent...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Singh, Swati, Khare, Garima, Bahal, Ritika Kar, Ghosh, Prahlad C, Tyagi, Anil K
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5935190/
https://ncbi.nlm.nih.gov/pubmed/29750019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S144240
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