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bioA mutant of Mycobacterium tuberculosis shows severe growth defect and imparts protection against tuberculosis in guinea pigs

Owing to the devastation caused by tuberculosis along with the unsatisfactory performance of the Bacillus Calmette–Guérin (BCG) vaccine, a more efficient vaccine than BCG is required for the global control of tuberculosis. A number of studies have demonstrated an essential role of biotin biosynthesi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kar, Ritika, Nangpal, Prachi, Mathur, Shubhita, Singh, Swati, Tyagi, Anil K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489182/
https://ncbi.nlm.nih.gov/pubmed/28658275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179513
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