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Unraveling the role of the transcriptional regulator VirS in low pH–induced responses of Mycobacterium tuberculosis and identification of VirS inhibitors

The ability of Mycobacterium tuberculosis to respond and adapt to various stresses such as oxygen/nitrogen radicals and low pH inside macrophages is critical for the persistence of this human pathogen inside its host. We have previously shown that an AraC/XylS-type transcriptional regulator, VirS, w...

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Vydáno v:J Biol Chem
Hlavní autoři: Singh, Swati, Goswami, Nikita, Tyagi, Anil K., Khare, Garima
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6664167/
https://ncbi.nlm.nih.gov/pubmed/31126988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005312
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