Pharmacokinetic Interaction between Maraviroc and Fosamprenavir-Ritonavir: an Open-Label, Fixed-Sequence Study in Healthy Subjects

This open-label, fixed-sequence, phase 1 study evaluated the pharmacokinetic interaction between maraviroc (MVC) and ritonavir-boosted fosamprenavir (FPV/r) in healthy subjects. In period 1, subjects received 300 mg of MVC twice daily (BID; cohort 1) or once daily (QD; cohort 2) for 5 days. In perio...

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Bibliographic Details
Main Authors: Vourvahis, Manoli, Plotka, Anna, Mendes da Costa, Laure, Fang, Annie, Heera, Jayvant
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837847/
https://ncbi.nlm.nih.gov/pubmed/24080663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01098-13
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