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Regiospecificities and Prenylation Mode Specificities of the Fungal Indole Diterpene Prenyltransferases AtmD and PaxD

We recently reported the function of paxD, which is involved in the paxilline (compound 1) biosynthetic gene cluster in Penicillium paxilli. Recombinant PaxD catalyzed a stepwise regular-type diprenylation at the 21 and 22 positions of compound 1 with dimethylallyl diphosphate (DMAPP) as the prenyl...

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Autors principals: Liu, Chengwei, Minami, Atsushi, Noike, Motoyoshi, Toshima, Hiroaki, Oikawa, Hideaki, Dairi, Tohru
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837767/
https://ncbi.nlm.nih.gov/pubmed/24038699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02496-13
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