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An analysis of the role of a retroendocytosis pathway in ABCA1-mediated cholesterol efflux from macrophages

The ATP binding cassette transporter A-1 (ABCA1) is critical for apolipoprotein-mediated cholesterol efflux, an important mechanism employed by macrophages to avoid becoming lipid-laden foam cells, the hallmark of early atherosclerotic lesions. It has been proposed that lipid-free apolipoprotein A-I...

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Hlavní autoři: Faulkner, Loren E., Panagotopulos, Stacey E., Johnson, Jacob D., Woollett, Laura A., Hui, David Y., Witting, Scott R., Maiorano, J. Nicholas, Davidson, W. Sean
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837451/
https://ncbi.nlm.nih.gov/pubmed/18359958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M800048-JLR200
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