Low Dose Bexarotene Treatment Rescues Dopamine Neurons and Restores Behavioral Function in Models of Parkinson’s Disease

[Image: see text] Nurr1 is a nuclear hormone receptor (NucHR) strongly implicated in the growth, maintenance, and survival of dopaminergic neurons. Nurr1 may be unable to bind ligands directly, but it forms heterodimers with other NucHRs that do. Using bioluminescence resonance energy transfer (BRET...

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Detalhes bibliográficos
Main Authors: McFarland, Krista, Spalding, Tracy A., Hubbard, David, Ma, Jian-Nong, Olsson, Roger, Burstein, Ethan S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2013
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837375/
https://ncbi.nlm.nih.gov/pubmed/24117438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn400100f
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