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An extended transcriptional network for pluripotency of embryonic stem cells

A regulatory network comprised of “core” (Oct4, Sox2, Nanog) and other transcription factors maintains embryonic stem (ES) cells in a self-renewing and pluripotent state. To develop an expanded framework with which to understand how these properties of ES cells are controlled, we have employed a mod...

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Detalles Bibliográficos
Main Authors: Kim, Jonghwan, Chu, Jianlin, Shen, Xiaohua, Wang, Jianlong, Orkin, Stuart H.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837340/
https://ncbi.nlm.nih.gov/pubmed/18358816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.02.039
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