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Global transcription in pluripotent embryonic stem cells

The molecular mechanisms underlying pluripotency and lineage specification from embryonic stem (ES) cells are largely unclear. Differentiation pathways may be determined by the targeted activation of lineage specific genes or by selective silencing of genome regions during differentiation. Here we s...

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Detalhes bibliográficos
Main Authors: Efroni, Sol, Duttagupta, Radharani, Cheng, Jill, Dehghani, Hesam, Hoeppner, Daniel J., Dash, Chandravanu, Bazett-Jones, David P., Le Grice, Stuart, McKay, Ronald D. G., Buetow, Kenneth H., Gingeras, Thomas R., Misteli, Tom, Meshorer, Eran
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2435228/
https://ncbi.nlm.nih.gov/pubmed/18462694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2008.03.021
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