A Myc rather than core pluripotency module accounts for the shared signatures of embryonic stem and cancer cells

c-Myc (Myc) is an important transcriptional regulator in embryonic stem (ES) cells, somatic cell reprogramming, and cancer. Here, we identify a Myc-centered regulatory network in ES cells by combining protein-protein and protein-DNA interaction studies, and show that Myc interacts with the NuA4 comp...

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Detalhes bibliográficos
Main Authors: Kim, Jonghwan, Woo, Andrew J., Chu, Jianlin, Snow, Jonathan W., Fujiwara, Yuko, Kim, Chul Geun, Cantor, Alan B., Orkin, Stuart H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018841/
https://ncbi.nlm.nih.gov/pubmed/20946988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.09.010
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