(E)-5-(2-Bromovinyl)-2'-deoxyuridine: a potent and selective anti-herpes agent.

Of a series of five newly synthesized 2'-deoxyuridine derivatives, including 5-vinyl-dUrd, 5-ethynyl-dUrd, 5-(1-chlorovinyl)-dUrd, (E)-5-(2-bromovinyl)-dUrd, and (E)-5-(2-iodovinyl)-dUrd, the last two compounds were found to exert a marked inhibitory effect on the replication of herpes simplex...

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Bibliografische gegevens
Hoofdauteurs: De Clercq, E, Descamps, J, De Somer, P, Barr, P J, Jones, A S, Walker, R T
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1979
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC383727/
https://ncbi.nlm.nih.gov/pubmed/223163
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