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Crystal Structure of Anti-polysialic Acid Antibody Single Chain Fv Fragment Complexed with Octasialic Acid: INSIGHT INTO THE BINDING PREFERENCE FOR POLYSIALIC ACID
Polysialic acid is a linear homopolymer of α2–8-linked sialic acids attached mainly onto glycoproteins. Cell surface polysialic acid plays roles in cell adhesion and differentiation events in a manner that is often dependent on the degree of polymerization (DP). Anti-oligo/polysialic acid antibodies...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3837122/ https://ncbi.nlm.nih.gov/pubmed/24100042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.496224 |
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