Cutting Edge: Bacterial Infection Induces Hematopoietic Stem and Progenitor Cell Expansion in the Absence of TLR Signaling

Bone marrow (BM) hematopoietic stem and progenitor cells (HSPCs) can be activated by type I IFNs, TLR agonists, viruses, and bacteria to increase hematopoiesis. In this study, we report that endotoxin treatment in vivo induces TLR4, MyD88, and Toll/IL-1 resistance domain-containing adaptor-inducing...

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Bibliographic Details
Main Authors: Scumpia, Philip O., Kelly-Scumpia, Kindra M., Delano, Matthew J., Weinstein, Jason S., Cuenca, Alex G., Al-Quran, Samer, Bovio, Ian, Akira, Shizuo, Kumagai, Yutaro, Moldawer, Lyle L.
Format: Artigo
Language:Inglês
Published: 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837089/
https://ncbi.nlm.nih.gov/pubmed/20130216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903652
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