PPARα and Sirt1 Mediate Erythropoietin Action in Increasing Metabolic Activity and Browning of White Adipocytes to Protect Against Obesity and Metabolic Disorders

Erythropoietin (EPO) has shown beneficial effects in the regulation of obesity and metabolic syndrome; however, the detailed mechanism is still largely unknown. Here, we created mice with adipocyte-specific deletion of EPO receptor. These mice exhibited obesity and decreased glucose tolerance and in...

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Main Authors: Wang, Li, Teng, Ruifeng, Di, Lijun, Rogers, Heather, Wu, Hong, Kopp, Jeffrey B., Noguchi, Constance Tom
格式: Artigo
語言:Inglês
出版: American Diabetes Association 2013
主題:
Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837041/
https://ncbi.nlm.nih.gov/pubmed/23990359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0518
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