PPARα and Sirt1 Mediate Erythropoietin Action in Increasing Metabolic Activity and Browning of White Adipocytes to Protect Against Obesity and Metabolic Disorders

Erythropoietin (EPO) has shown beneficial effects in the regulation of obesity and metabolic syndrome; however, the detailed mechanism is still largely unknown. Here, we created mice with adipocyte-specific deletion of EPO receptor. These mice exhibited obesity and decreased glucose tolerance and in...

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Détails bibliographiques
Auteurs principaux: Wang, Li, Teng, Ruifeng, Di, Lijun, Rogers, Heather, Wu, Hong, Kopp, Jeffrey B., Noguchi, Constance Tom
Format: Artigo
Langue:Inglês
Publié: American Diabetes Association 2013
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837041/
https://ncbi.nlm.nih.gov/pubmed/23990359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0518
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