PPARα and Sirt1 Mediate Erythropoietin Action in Increasing Metabolic Activity and Browning of White Adipocytes to Protect Against Obesity and Metabolic Disorders

Erythropoietin (EPO) has shown beneficial effects in the regulation of obesity and metabolic syndrome; however, the detailed mechanism is still largely unknown. Here, we created mice with adipocyte-specific deletion of EPO receptor. These mice exhibited obesity and decreased glucose tolerance and in...

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Detalhes bibliográficos
Main Authors: Wang, Li, Teng, Ruifeng, Di, Lijun, Rogers, Heather, Wu, Hong, Kopp, Jeffrey B., Noguchi, Constance Tom
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837041/
https://ncbi.nlm.nih.gov/pubmed/23990359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0518
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