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Harnessing Gene Conversion in Chicken B Cells to Create a Human Antibody Sequence Repertoire

Transgenic chickens expressing human sequence antibodies would be a powerful tool to access human targets and epitopes that have been intractable in mammalian hosts because of tolerance to conserved proteins. To foster the development of the chicken platform, it is beneficial to validate transgene c...

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Detalhes bibliográficos
Main Authors: Schusser, Benjamin, Yi, Henry, Collarini, Ellen J., Izquierdo, Shelley Mettler, Harriman, William D., Etches, Robert J., Leighton, Philip A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837002/
https://ncbi.nlm.nih.gov/pubmed/24278246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080108
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