Heparin Modulates the Endopeptidase Activity of Leishmania mexicana Cysteine Protease Cathepsin L-Like rCPB2.8

BACKGROUND: Cysteine protease B is considered crucial for the survival and infectivity of the Leishmania in its human host. Several microorganism pathogens bind to the heparin-like glycosaminoglycans chains of proteoglycans at host-cell surface to promote their attachment and internalization. Here,...

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Detalhes bibliográficos
Main Authors: Judice, Wagner A. S., Manfredi, Marcella A., Souza, Gerson P., Sansevero, Thiago M., Almeida, Paulo C., Shida, Cláudio S., Gesteira, Tarsis F., Juliano, Luiz, Westrop, Gareth D., Sanderson, Sanya J., Coombs, Graham H., Tersariol, Ivarne L. S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836952/
https://ncbi.nlm.nih.gov/pubmed/24278253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080153
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