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α-Ketoheterocycles as inhibitors of Leishmania mexicana cysteine protease CPB
Cysteine proteases of the papain superfamily are present in nearly all eukaryotes and also play pivotal roles in the biology of parasites. Inhibition of cysteine proteases is emerging as an important strategy to combat parasitic diseases such as sleeping sickness, Chagas’ disease and leishmaniasis....
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| Главные авторы: | , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3245848/ https://ncbi.nlm.nih.gov/pubmed/20799311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201000265 |
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