Transcriptional environment and chromatin architecture interplay dictates globin expression patterns of heterospecific hybrids derived from undifferentiated human embryonic stem cells or from their erythroid progeny

To explore the response of β globin locus with established chromatin domains upon their exposure to new transcriptional environments, we transferred the chromatin-packaged β globin locus of undifferentiated hESCs or hESC-derived erythroblasts into an adult transcriptional environment. Distinct globi...

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Detalhes bibliográficos
Main Authors: Chang, Kai-Hsin, Huang, Andy, Han, Hemei, Jiang, Yi, Fang, Xiangdong, Song, Chao-Zhong, Padilla, Steve, Wang, Hao, Qu, Hongzhu, Stamatoyannopoulos, John, Li, Qiliang, Papayannopoulou, Thalia
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836866/
https://ncbi.nlm.nih.gov/pubmed/23993951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2013.08.005
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