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Understanding the Connection between Epigenetic DNA Methylation and Nucleosome Positioning from Computer Simulations
Cytosine methylation is one of the most important epigenetic marks that regulate the process of gene expression. Here, we have examined the effect of epigenetic DNA methylation on nucleosomal stability using molecular dynamics simulations and elastic deformation models. We found that methylation of...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3836855/ https://ncbi.nlm.nih.gov/pubmed/24278005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003354 |
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