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Understanding the Connection between Epigenetic DNA Methylation and Nucleosome Positioning from Computer Simulations
Cytosine methylation is one of the most important epigenetic marks that regulate the process of gene expression. Here, we have examined the effect of epigenetic DNA methylation on nucleosomal stability using molecular dynamics simulations and elastic deformation models. We found that methylation of...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3836855/ https://ncbi.nlm.nih.gov/pubmed/24278005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003354 |
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