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Chromatin unfolding by epigenetic modifications explained by dramatic impairment of internucleosome interactions: a multiscale computational study

Histone tails and their epigenetic modifications play crucial roles in gene expression regulation by altering the architecture of chromatin. However, the structural mechanisms by which histone tails influence the interconversion between active and inactive chromatin remain unknown. Given the technic...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Collepardo-Guevara, Rosana, Portella, Guillem, Vendruscolo, Michele, Frenkel, Daan, Schlick, Tamar, Orozco, Modesto
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6251407/
https://ncbi.nlm.nih.gov/pubmed/26192632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b04086
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