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Chromatin unfolding by epigenetic modifications explained by dramatic impairment of internucleosome interactions: a multiscale computational study

Histone tails and their epigenetic modifications play crucial roles in gene expression regulation by altering the architecture of chromatin. However, the structural mechanisms by which histone tails influence the interconversion between active and inactive chromatin remain unknown. Given the technic...

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Détails bibliographiques
Publié dans:J Am Chem Soc
Auteurs principaux: Collepardo-Guevara, Rosana, Portella, Guillem, Vendruscolo, Michele, Frenkel, Daan, Schlick, Tamar, Orozco, Modesto
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6251407/
https://ncbi.nlm.nih.gov/pubmed/26192632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b04086
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