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Role of Cross-Cleft Contacts in NMDA Receptor Gating

In response to brief glutamate exposure, NMDA receptors produce excitatory currents that have sub-maximal amplitudes and characteristically slow kinetics. The activation sequence starts when glutamate binds to residues located on the upper lobe of extracellularly located ligand-binding domains (LBDs...

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Bibliografske podrobnosti
Main Authors: Paganelli, Meaghan A., Kussius, Cassandra L., Popescu, Gabriela K.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836766/
https://ncbi.nlm.nih.gov/pubmed/24278352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080953
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