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Role of Cross-Cleft Contacts in NMDA Receptor Gating
In response to brief glutamate exposure, NMDA receptors produce excitatory currents that have sub-maximal amplitudes and characteristically slow kinetics. The activation sequence starts when glutamate binds to residues located on the upper lobe of extracellularly located ligand-binding domains (LBDs...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3836766/ https://ncbi.nlm.nih.gov/pubmed/24278352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080953 |
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