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Pregnanolone Sulfate Promotes Desensitization of Activated NMDA Receptors

Neurosteroids are potent neuromodulators which act in part by binding to and modifying the activity of neurotransmitter-gated channels. Pregnanolone sulfate (PAS) is an endogenous neurosteroid that inhibits NMDA receptors and is neuroprotective in vivo. To delineate the mechanism of NMDA receptor in...

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Autors principals: Kussius, Cassandra L., Kaur, Navjot, Popescu, Gabriela K.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150747/
https://ncbi.nlm.nih.gov/pubmed/19474309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0281-09.2009
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