Deciphering the genetic architecture of low-penetrance susceptibility to colorectal cancer

Recent genome-wide association studies (GWASs) have identified common variants at 16 autosomal regions influencing the risk of developing colorectal cancer (CRC). To decipher the genetic basis of the association signals at these loci, we performed a meta-analysis of data from five GWASs, totalling 5...

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Detalhes bibliográficos
Main Authors: Whiffin, Nicola, Dobbins, Sara E., Hosking, Fay J., Palles, Claire, Tenesa, Albert, Wang, Yufei, Farrington, Susan M., Jones, Angela M., Broderick, Peter, Campbell, Harry, Newcomb, Polly A., Casey, Graham, Conti, David V., Schumacher, Fred, Gallinger, Steve, Lindor, Noralane M., Hopper, John, Jenkins, Mark, Dunlop, Malcolm G., Tomlinson, Ian P., Houlston, Richard S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Association Studies Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836483/
https://ncbi.nlm.nih.gov/pubmed/23904454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt357
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