Biochemical basis for differential deoxyadenosine toxicity to T and B lymphoblasts: role for 5'-nucleotidase.

Deoxyadenosine metabolism was investigated in cultured human cells to elucidate the biochemical basis for the sensitivity of T lymphoblasts and the resistance of B lymphoblasts to deoxyadenosine toxicity. T lymphoblasts have a 20-to 45-fold greater capacity to synthesize deoxyadenosine nucleotides t...

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Bibliographische Detailangaben
Hauptverfasser: Wortmann, R L, Mitchell, B S, Edwards, N L, Fox, I H
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1979
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC383616/
https://ncbi.nlm.nih.gov/pubmed/221924
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