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Biochemical basis for differential deoxyadenosine toxicity to T and B lymphoblasts: role for 5'-nucleotidase.

Deoxyadenosine metabolism was investigated in cultured human cells to elucidate the biochemical basis for the sensitivity of T lymphoblasts and the resistance of B lymphoblasts to deoxyadenosine toxicity. T lymphoblasts have a 20-to 45-fold greater capacity to synthesize deoxyadenosine nucleotides t...

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Main Authors: Wortmann, R L, Mitchell, B S, Edwards, N L, Fox, I H
格式: Artigo
語言:Inglês
出版: 1979
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC383616/
https://ncbi.nlm.nih.gov/pubmed/221924
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