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Partial deletion of beta-globin gene DNA in certain patients with beta 0-thalassemia.

We have used restriction endonuclease mapping of cell DNA to investigate the structure of the beta-globin gene in beta-thalassemias. Among 17 individuals with beta +- and beta 0-thalassemia, we observed three patients of Indian origin with beta 0-thalassemia whose DNA revealed a consistent mapping a...

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Autors principals: Orkin, S H, Old, J M, Weatherall, D J, Nathan, D G
Format: Artigo
Idioma:Inglês
Publicat: 1979
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC383609/
https://ncbi.nlm.nih.gov/pubmed/287080
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