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Partial deletion of beta-globin gene DNA in certain patients with beta 0-thalassemia.

We have used restriction endonuclease mapping of cell DNA to investigate the structure of the beta-globin gene in beta-thalassemias. Among 17 individuals with beta +- and beta 0-thalassemia, we observed three patients of Indian origin with beta 0-thalassemia whose DNA revealed a consistent mapping a...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Orkin, S H, Old, J M, Weatherall, D J, Nathan, D G
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1979
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383609/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/287080/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.5.2400
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