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Heterogeneity of DNA deletion in gamma delta beta-thalassemia.

By restriction endonuclease mapping, gene cloning, and DNA sequencing we have determined the region of DNA that is deleted in a family with gamma delta beta-thalassemia. The deletion removes the linked epsilon, gamma-, and delta-globin structural genes and terminates within the coding portion of the...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Orkin, S H, Goff, S C, Nathan, D G
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1981
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370639/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6162860/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110105
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