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AGO61-dependent GlcNAc modification primes the formation of functional glycans on α-dystroglycan
Dystroglycanopathy is a major class of congenital muscular dystrophy that is caused by a deficiency of functional glycans on α-dystroglycan (α-DG) with laminin-binding activity. A product of a recently identified causative gene for dystroglycanopathy, AGO61, acted in vitro as a protein O-mannose β-1...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3836086/ https://ncbi.nlm.nih.gov/pubmed/24256719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03288 |
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