Pancreatic Duct Ligation After Almost Complete β-Cell Loss: Exocrine Regeneration but No Evidence of β-Cell Regeneration

There has been great interest in the extent of β-cell regeneration after pancreatic duct ligation (PDL) and whether α- to β-cell conversion might account for β-cell regeneration after near-complete β-cell loss. To assess these questions, we established a PDL-model in adult male rats after almost com...

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Main Authors: Cavelti-Weder, Claudia, Shtessel, Maria, Reuss, Joshua E., Jermendy, Agnes, Yamada, Takatsugu, Caballero, Francisco, Bonner-Weir, Susan, Weir, Gordon C.
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2013
Fag:
Diabetes-Insulin-Glucagon-Gastrointestinal
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836076/
https://ncbi.nlm.nih.gov/pubmed/24029238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2013-1463
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