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JNK Expression by Macrophages Promotes Obesity-induced Insulin Resistance and Inflammation
The cJun NH(2)-terminal kinase (JNK) signaling pathway contributes to inflammation and plays a key role in the metabolic response to obesity, including insulin resistance. Macrophages are implicated in this process. To test the role of JNK, we established mice with selective JNK-deficiency in macrop...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3835653/ https://ncbi.nlm.nih.gov/pubmed/23223452 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1227568 |
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