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Inflammation mediated by JNK in myeloid cells promotes the development of hepatitis and hepatocellular carcinoma

The cJun NH(2)-terminal kinase (JNK) signaling pathway is required for the development of hepatitis and hepatocellular carcinoma. A role for JNK in liver parenchymal cells has been proposed, but more recent studies have implicated non-parenchymal liver cells as the relevant site of JNK signaling. He...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Han, Myoung Sook, Barrett, Tamera, Brehm, Michael A., Davis, Roger J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826851/
https://ncbi.nlm.nih.gov/pubmed/27052181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.03.008
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