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A Synthesis of the Chlorosulfolipid Mytilipin A via a Longest Linear Sequence of Seven Steps

The chlorosulfolipid mytilipin A has been synthesized in racemic form in only seven steps and in enantioenriched form in eight steps. Key transformations include a highly diastereoselective bromoallylation of a sensitive α,β-dichloroaldehyde, a kinetic resolution of a complex vinyl epoxide, a conver...

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Detalhes bibliográficos
Main Authors: Chung, Won-jin, Carlson, Joseph S., Bedke, D. Karl, Vanderwal, Christopher D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835569/
https://ncbi.nlm.nih.gov/pubmed/23929596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201304565
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